Luminal alkalinization by guinea-pig cecum in vitro,an electro-neutral process |
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| Authors: | D W Watkins W L Pintauro |
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| Institution: | (1) Department of Physiology, George Washington University School of Medicine, 2300 Eye Street N. W., 20037 Washington, DC, USA |
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| Abstract: | Summary Guinea-pig cecum was found to alkalinize its mucosal media in vitro at a chemical equivalents rate greater than the short circuit current (ISC). Alkalinization was inhibited by conditions which did not affect ISC and by low mucosal Na suggesting an electro-neutral process, dependent on Na.This study was supported in part by the National Science Foundation Grant BMS 74-08901. The authors appreciate the insight and encouragement of Dr Michael J. Jackson expressed in numerous conversations. |
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