Molecular recognition: Models for drug design |
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Authors: | R. J. Breckenridge |
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Affiliation: | 1. Drug Design Group, Sandoz Pharma Ltd., CH-4002, Basel, (Switzerland)
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Abstract: | The review takes examples, mostly from the recent literature, to illustrate how an understanding of physico-chemical properties and an appreciation of the molecular shape and electronic properties can lead to a better insight into molecular recognition processes. The techniques used to generate 3-dimensional structures of molecules and the influence this information has had on the drug design cycle, are briefly discussed. |
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