Prolongation of the survival of skin grafts in mice by PUVA treatment |
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| Authors: | S Gruner C Riese S Schnitzler H Meffert E Karasek |
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| Institution: | (1) Abt. Klinische Immunologie und Hautklinik, Bereich Medizin (Charité) der Humboldt-Universität, Postfach 170, DDR-1040 Berlin, (German Democratic Republic);(2) Abt. für Versuchstierzucht des Forschungszentrums für Molekularbiologie und Medizin der Akademie der Wissenschaften der DDR, (German Democratic Republic) |
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| Abstract: | Summary The combined application of psoralen and UVA radiation to skin grafts induced a prolongation of the survival time of the grafts in mice. This was observed using the H-Y barrier, an allogeneic barrier without H-2 disparities, and a strong H-2 incompatible barrier. The effect is probably due to a reduction of antigen-presenting cells, or to other, unknown mechanisms. |
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