Release of immuno-reactive and biologically active LH from fetal mouse pituitary in response to synthetic gonadotropin releasing factor (LRF) |
| |
| Authors: | G Pointis J A Mahoudeau |
| |
| Institution: | (1) Laboratoire de Chimie Hormonale, Maternité de Port-Royal, F-75014 Paris, (France);(2) Present address: Centre de Recherches Endocrinologiques, Hôpital Cochin, 27, rue du Faubourg Saint-Jacques, F-75014 Paris, (France);(3) Present address: Laboratoire d'Histophysiologie du Collège de France, 4, avenue Gordon-Bennett, 75016 Paris, France |
| |
| Abstract: | Summary In an incubation system, LRF stimulated significantly the release of LH from 18-day-old mouse fetal pituitary. This LRF-induced LH release, measured by RIA in the incubation medium was able to increase the testosterone production by age-matched fetal testes. This data suggests that the hypothalamo-hypophyseal-testicular axis is functional at the end of mouse prenatal life.The expert technical assistance of MrsM. T. Latreille andA. L'Héritier are grafefully acknowledged. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
