| 一种新型两性离子交换毛细管液相色谱整体柱 |
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| 引用本文： | 李金祥,房晶,谢文辉. 一种新型两性离子交换毛细管液相色谱整体柱[J]. 辽宁师范大学学报(自然科学版), 2010, 33(1) |
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| 作者姓名： | 李金祥 房晶 谢文辉 |
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| 作者单位： | 辽宁师范大学,化学化工学院,辽宁,大连,116029 |
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| 基金项目： | 辽宁省自然科学基金项目(2050815) |
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| 摘 要： | 利用甲基丙烯酸和2-二甲基乙基胺甲基丙烯酸酯为功能单体,乙二醇二甲基丙烯酸酯为交联剂,通过在石英毛细管内原位聚合制备了1种新型两性离子交换液相色谱整体(MAA-EDMA-DAMA)柱.整体固定相表面正、负电荷密度受流动相pH影响,故通过调节流动相pH值可实现阴阳离子交换模式相互转换.当流动相pH6.0时,此整体柱表现出典型阴离子交换作用机理,聚合整体柱对一些无机阴离子如BrO3-、NO2-、Br-和NO3-有很好的选择性;当流动相pH7.0时,该整体柱表现出阳离子交换作用机理,对对甲苯胺、邻苯二胺、对氯苯胺、对硝基苯胺表现出高的选择性;当流动相中乙腈含量小于40%时,疏水作用和离子交换作用对有机离子的保留均有影响,为提高分离的选择性创造有利条件.
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| 关 键 词： | 毛细管液相色谱 整体柱 两性离子交换 |
A novel zwitterionic monolithic stationary phase for capillary liquid chromatography |
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| LI Jin-xiang,FANG Jing,XIE Wen-hui. A novel zwitterionic monolithic stationary phase for capillary liquid chromatography[J]. Journal of Liaoning Normal University(Natural Science Edition), 2010, 33(1) |
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| Authors: | LI Jin-xiang FANG Jing XIE Wen-hui |
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| Affiliation: | School of Chemistry and Chemical Engineering/a>;Liaoning Normal University/a>;Dalian 116029/a>;China |
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| Abstract: | A novel zwitterionic monolithic stationary phase was prepared for capillary liquid chromatography by in-situ polymerization of methacrylic acid,ethylene dimetharylate and 2-(dimethyl amino)ethyl methacrylate in the presence of porogens.The density of positive and negative charges on the stationary phase can be affected by the pH values of mobile phase,thus the cation-anion ion-exchange modes can be converted mutually by simply adjusting the pH value of the mobile phase.A typical anion ion-exchange interacti... |
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| Keywords: | capillary liquid chromatography zwitterionic stationary phase ion-exchange |
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