Somatostatin reduces the release of colony-stimulating activity (CSA) from PHA-activated mouse spleen lymphocytes |
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Authors: | W Hinterberger C Cerny H Kinast H Pointner K H Tragl |
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Institution: | (1) 1st Dept. of Medicine, University of Vienna, Lazarettgasse 14, A-1090 Wien, (Austria) |
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Abstract: | Summary PHA-activated lymphocytes release colony-stimulating activity (CSA) for macrophage-granulocyte precursor cells (colony forming units, CFUC) in the culture medium. Somatostatin, known to interfer with ribosomal protein synthesis, was demonstrated to reduce the release of CSA from PHA-treated mouse spleen lymphocytes.The technical assistance of Ulrike Wallner and Paulette Bais is thankfully acknowledged. |
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