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Somatostatin reduces the release of colony-stimulating activity (CSA) from PHA-activated mouse spleen lymphocytes
Authors:W Hinterberger  C Cerny  H Kinast  H Pointner  K H Tragl
Institution:(1) 1st Dept. of Medicine, University of Vienna, Lazarettgasse 14, A-1090 Wien, (Austria)
Abstract:Summary PHA-activated lymphocytes release colony-stimulating activity (CSA) for macrophage-granulocyte precursor cells (colony forming units, CFUC) in the culture medium. Somatostatin, known to interfer with ribosomal protein synthesis, was demonstrated to reduce the release of CSA from PHA-treated mouse spleen lymphocytes.The technical assistance of Ulrike Wallner and Paulette Bais is thankfully acknowledged.
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