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Evidence for existence of pores in intramembranous particles revealed by freeze fracturing]
Authors:L Orci  A Perrelet  F Malaisse-Lagae  P Vassalli
Abstract:In freeze-fracture replicas of membranes (plasma and intracellular) in a variety of animal cells, it is possible to detect the presence of intramembrane particles containing an electron-dense spot. The spot is interpreted as an accumulation of platinum into a cavity; the cavity could in turn correspond to a hydrophilic pore in the particle.
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