Ⅱ型糖尿病骨质疏松与血管钙化的相关性分析

目的分析Ⅱ型糖尿病患者骨质疏松和骨量减少与血管钙化之间的关联性，为早期诊断和预防糖尿病性骨质疏松提供依据．方法按入选标准对59例Ⅱ型糖尿病患者记录临床体征、血液实验室检查结果．采用双能x线吸收法测定腰椎和股骨颈骨密度值，x线摄片记录胸主动脉和髂动脉的血管钙化情况，并对各因素与糖尿病性骨质疏松相关性进行分析．结果腰椎骨量分析可见：骨质疏松6例（10．2％），骨量减少27例（45．8％）；股骨颈骨量分析可见：骨质疏松7例（11．8％），骨量减少28例（49％）．髂动脉钙化与腰椎（L1—L4）骨质疏松（P=0．04）和股骨颈骨质疏松（P=0．036）存在显著相关性．结论Ⅱ型糖尿病患者髂动脉钙化与骨质疏松呈正相关，发现动脉钙化可能提示骨质疏松或骨量减少的存在．

Correlation Analysis of Vascular Calcification and Osteoporosis in Patients with Type 2 Diabetic

Objective To evaluate the correlation between osteoporosis and arterial calcification and osteopenia so as to provide an evidence for the early diagnosis and prevention of osteoporosis complicated with T2DM.Method Clinical signs and laboratory blood results of 59 patients with type 2 diabetes mellitus diagnosed based on the selected criterion were recorded.The bone density of all patients’ lumbar vertebra and neck of femur were assessed with dual-energy X-ray absorptiometry,the vascular calcification of thoracic aorta and iliac artery of the patients were identified with X-ray,and the correlation between the osteoporosis complicated with diabetes mellitus and the various factors were analyzed.Result The analysis of lumbar vertebra bone mass showed that 6 cases(10.2%)of them were found to have osteoporosis in the lumbar spine and 27cases(45.8%) osteopenia;The analysis neck bone mass showed that there were 7 patients(11.8%) with osteoporosis and 28(49%) with osteopenia.There was a significant correlation between the iliac artery calcification and osteoporosis in the lumbar spine L1-L4(P=0.004) or in the femoral neck(P=0.036).Conclusion There was a positive correlation between the iliac artery calcification and osteoporosis in type 2 patients,the presence of arterial calcification may indicate the presence of osteoporosis.