Prostaglandin A2 (PGA2) increases the coronary vascular resistance in the guinea-pig isolated heart preparation |
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Authors: | K. Schrör R. Krebs |
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Affiliation: | (1) Pharmakologisches Institut der Universität Mainz, Obere Zahlbacher Strasse 67, D-6500 Mainz, Federal Republic of Germany, BRD |
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Abstract: | Summary Prostaglandin A2 (PGA2) in concentrations of 1.5·10–8 to 3·10–6 M was found to produce concentration-dependent increase in the coronary vascular resistance of the guinea-pig isolated heart without alterations in myocardial contractile force and oxygen consumption.Supported by the Deutsche Forschungsgemeinschaft. |
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