The effect of postnatal undernourishment on epileptiform kindling of dorsal hippocampus |
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| Authors: | Katherine H Taber G N Fuller J C Stanley J F DeFrance R C Wiggins |
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| Institution: | (1) Department of Neurobiology and Anatomy, University of Texas Medical School at Houston, P.O. Box 20708, 77025 Houston, Texas, USA |
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| Abstract: | Summary Rats were undernourished postnatally from birth through 20 days of age. They were subsequently tested for susceptibility to motor seizures kindled in hippocampus in adulthood. Compared to littermate control animals the postnatally undernourished rats were more susceptible to the kindling treatment. We conclude that early postnatal undernourishment has a permanent effect on susceptibility of the hippocampus to electrically-induced seizures.This work was supported by Public Health Service grant NS 13799, National Science Foundation grant GB 35532, and by Hoffman-LaRoche, Inc. |
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