Genomic sequence determination of Classical Swine Fever Virus persistent infection strain

Full genomic sequence of a newly isolated persistent infection strain of classical swine fever virus was firstly determined. It was demonstrated by sequence analyses that nucleotides homologies of this strain compared with virulent Shimen and vaccine HCLV were 89.7% and 87.7%, and homologies of amino acids were 94.8% and 93.3%, respectively. The sequencing results primarily suggest a tighter relationship between this persistent infection strain and virulent Shimen strain than vaccine HCLV strain. Foundation item: Supported by National Basic Research Developmental Project (G199911900). GenBank NO.: AF407339 Biography: Wu Hai-xiang (1976-), Ph.D. candidate, research direction: virus genetics.