The signal transducing system coupled to serotonin-S2 receptors |
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| Authors: | D de Chaffoy de Courcelles J E Leysen F de Clerck |
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| Affiliation: | Department of Biochemistry, Janssen Pharmaceutica Research Laboratories, Beerse, Belgium. |
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| Abstract: | The signal transducing system coupled to the serotonin-S2 receptor on platelets involves metabolism of inositol-containing phospholipid, elevation of intracellular free Ca2+ and activation of protein kinase C. Evidence for coupling of the serotonin-S2 receptor to the same signal transducing system in brain and smooth muscle tissue is reviewed. |
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