In vitro assessment of anti-Leishmania immunity of man acquired with a vaccine |
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| Authors: | I Vouldoukis B W Ogunkolade D Frommel N Alier L Monjour |
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| Institution: | (1) Laboratoire de Parasitologie Expérimentale et INSERM Unité 313, Faculté de Médecine Pitié-Salpêtrière, 91, Bd de l'Hôpital, F-75013 Paris, France |
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| Abstract: | Summary Monocytes, obtained from a human volunteer immunized with aLeishmania infantum-derived vaccine, when cultured in vitro displayed a strong parasiticidal activity againstL. major promastigotes. In addition, immune serum conferred leishmanicidal activities to monocytes of normal unexposed donors, and to murine macrophages. |
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| Keywords: | Leishmania infantum Leishmania major vaccine immunoprophylaxis |
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