| 微波辐射下固体酸催化合成异烟酸乙酯 |
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| 引用本文： | 沈阳,蒋华江.微波辐射下固体酸催化合成异烟酸乙酯[J].科学技术与工程,2009,9(16). |
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| 作者姓名： | 沈阳 蒋华江 |
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| 作者单位： | 台州学院医药化工学院,临海,31700 |
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| 摘 要： | 在微波辐射下,以异烟酸和乙醇为原料,以活性炭固载对甲苯磺酸作催化剂,合成了异烟酸乙酯.最佳工艺条件:醇酸物质的量比为8∶ 1,催化剂用量为 1.0 g,微波辐射时间为 10 min,微波辐射功率为 200 W,酯化产率达 97.18%.另外通过实验发现,微波辐射下,反应速率及产率都明显高于常规加热方式.
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| 关 键 词： | 微波辐射 异烟酸乙酯 固体酸 活性炭 对甲苯磺酸 |
Synthesis of Ethyl Isonicotinate Catalyzed by Solid Acid Supported on Activated Carbon under Microwave Irradiation |
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| SHEN Yang,JIANG Hua-jiang.Synthesis of Ethyl Isonicotinate Catalyzed by Solid Acid Supported on Activated Carbon under Microwave Irradiation[J].Science Technology and Engineering,2009,9(16). |
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| Authors: | SHEN Yang JIANG Hua-jiang |
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| Affiliation: | School of Pharmaceutical and Chemical Engineering;Taizhou University;Linhai 317000;P. R. China |
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| Abstract: | Under microwave irradiation,ethyl isonicotinate were synthesized using isonicotinic acid and anhydrous ethanol as raw materials catalyzed by p-toluenesulfonic acid supported on activated carbon. The optimum technological conditions were obtained:molar ratio of alcohol to acid was 8:1,amount of catalyst was 1.0g,and reaction time was 10 min,powers of microwave irradiation was 200W,the total yield was 97.18%. In addition,it was found that under microwave irradiation,the reaction rate of esterificat-ion and th... |
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| Keywords: | microwave irradiation ethyl isonicotinate solid acid activated carbon p-toluenesulfonic acid |
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