| 单克隆抗体在动物疫病防控中的应用 |
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| 引用本文： | 翟新验,刘钧. 单克隆抗体在动物疫病防控中的应用[J]. 实验动物科学, 2015, 32(2): 53-55 |
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| 作者姓名： | 翟新验 刘钧 |
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| 作者单位： | 中国动物疫病预防控制中心;北京市饲料监察所 |
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| 基金项目： | 科技基础性工作专项(No.2013FY113300-6);生猪产业技术体系北京市创新团队(No.GWZJ-2009-05) |
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| 摘 要： | 摘要: 单克隆抗体是应用聚乙二醇等融合剂将骨髓瘤细胞和经某种抗原诱导产生的特异性 B 淋巴细胞在体外进行细胞融合，产生能连续传代、稳定分泌特异抗体的杂交瘤细胞。随着单克隆抗体的广泛应用，其在动物疫病抗原表位和变异研究、感染机制研究、诊断检测和疫病治疗等方面发挥了积极作用。
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| 关 键 词： | 单克隆抗体 动物疫病 防控 |
Monoclonal Antibody Application on Prevention and Control of Animal Diseases |
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| ZHAI Xin-yan;LIU Jun. Monoclonal Antibody Application on Prevention and Control of Animal Diseases[J]. Laboratory Animal Science, 2015, 32(2): 53-55 |
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| Authors: | ZHAI Xin-yan LIU Jun |
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| Affiliation: | ZHAI Xin-yan;LIU Jun;China Animal Disease Control Center;Beijing Institute of Feed Surpervision; |
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| Abstract: | Abstract: Monoclonal antibody is hybridoma cell which fuses myeloma cell with specific lymphocyte B induced by certain antigen with the help of polyethylene glycol． The hybridoma cell can be serial passages and steadily secrete specific antibody． With the development of monoclonal antibody technology，it has been widely applied on animal disease prevention and control，for example，research on antigenic epitope and pathogen variation，as well as infectious mechanism，diagnosis，detection and treatment of animal diseases． Hence，monoclonal antibody plays vital role in preventive technique study of animal diseases． |
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| Keywords: | monoclonal antibody animal disease prevention and control |
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