Investigations on the turnover of adrenocortical mitochondria. VII. Effects of ACTH on the half-life of mitochondria from the zona reticularis of the rat adrenal cortex |
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| Authors: | C Robba G Mazzocchi A S Belloni A M Gambino G G Nussdorfer |
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| Institution: | (1) Department of Anatomy, Laboratory of Electron Microscopy, University of Padua, I-35100 Padova, (Italy) |
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| Abstract: | Summary The half-life of mitochondria from the zona reticularis of the rat adrenal was calculated by determining the radioactivity decay curves of the mitochondrial compartment of 3H-thymidine-injected animals, using autoradiographic methods. ACTH was found to enhance significantly the half-life of the organelles.Acknowledgment. We wish to thank Miss A. Coi and Mr G. Gottardo for the skilled techical assistance. This work was partly supported by a contract with the CNR (No. 74.00226.04/115.3439). |
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