| Preparation of bioactive glasses with controllable degradation behavior and their bioactive characterization |
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| 作者姓名： | YAO AiHua WANG DePing FU Qiang HUANG WenHai Mohamed N. RAHAMAN |
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| 作者单位： | [1]School of Materials Science and Technology, Tongji University, Shanghai 200092, China [2]University of Missouri-Rolla, MO 65409, USA |
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| 基金项目： | Supported by under Shanghai Key Fundamental Research Project （Grant No. 05DJ14006） and University of Missouri-Rolla. |
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| 摘 要： | Bioactive glasses and ceramics have been widely investigated for bone repair because of their excel-lent bioactive characteristics. However, these biomaterials undergo incomplete conversion into a bone-like material, which severely limits their biomedical application. In this paper, borosilicate bioac-tive glasses were prepared by traditional melting process. The results showed that borosilicate glasses possessed high biocompatibility and bioactivity. In addition, when immersed in a 0.02 mol/L K2HPO4 solution, particles of a borate glass were fully converted to HA. The desirable conversion rate to HA may be achieved through the adjustment of the B2O3/SiO2 ratio. The results of XRD and FTIR analysis indicated that the degradation product was carbonate-substituted hydroxyapatite, which was similar to the inorganic component of bone.
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| 关 键 词： | 生物活性 陶瓷 玻璃 降解行为 生物材料 骨组织 |
| 收稿时间： | 9 July 2006 |
| 修稿时间： | 2006-07-09 |
Preparation of bioactive glasses with controllable degradation behavior and their bioactive characterization |
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| YAO AiHua WANG DePing FU Qiang HUANG WenHai Mohamed N. RAHAMAN.Preparation of bioactive glasses with controllable degradation behavior and their bioactive characterization[J].Chinese Science Bulletin,2007,52(2):272-276. |
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| Authors: | Yao AiHua Wang DePing Fu Qiang Huang WenHai Mohamed N Rahaman |
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| Institution: | (1) School of Materials Science and Technology, Tongji University, Shanghai, 200092, China;(2) University of Missouri-Rolla, MO 65409, USA |
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| Abstract: | Bioactive glasses and ceramics have been widely investigated for bone repair because of their excel-lent bioactive characteristics. However, these biomaterials undergo incomplete conversion into a bone-like material, which severely limits their biomedical application. In this paper, borosilicate bioac-tive glasses were prepared by traditional melting process. The results showed that borosilicate glasses possessed high biocompatibility and bioactivity. In addition, when immersed in a 0.02 mol/L K2HPO4 solution, particles of a borate glass were fully converted to HA. The desirable conversion rate to HA may be achieved through the adjustment of the B2O3/SiO2 ratio. The results of XRD and FTIR analysis indicated that the degradation product was carbonate-substituted hydroxyapatite, which was similar to the inorganic component of bone. |
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| Keywords: | borosilicate glass bioactive glass biodegradation bioactivity |
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