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Evidence against prostaglandin E having a physiological role in acetylcholine liberation from Auerbach's plexus of guinea-pig ileum.
Authors:J Hazra
Abstract:The effect of INDO, a PGE synthesis inhibitor, on ACh output from Auerbach's plexus of guinea-pig ileum was investigated. INDO (15-45 mum/ml) failed to alter significantly either spontaneous ACh output or ACh output induced by field stimulation. It is concluded that PGE plays no physiological role in ACh liberation from this tissue.
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