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Induction of core symptoms of autism spectrum disorder by in vivo CRISPR/Cas9-based gene editing in the brain of adolescent rhesus monkeys |
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| Authors: | Shi-Hao Wu Xiao Li Dong-Dong Qin Lin-Heng Zhang Tian-Lin Cheng Zhi-Fang Chen Bin-Bin Nie Xiao-Feng Ren Jing Wu Wen-Chao Wang Ying-Zhou Hu Yi-Lin Gu Long-Bao Lv Yong Yin Xin-Tian Hu Zi-Long Qiu |
| Abstract: | Although CRISPR/Cas9-mediated gene editing is widely applied to mimic human disorders,whether acute manipulation of disease-causing genes in the brain leads to ... |
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