A possible genetic component of obesity in childhood. Observations on acid phosphatase polymorphism |
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| Authors: | N. Lucarini G. Finocchi F. Gloria-Bottini M. Macioce P. Borgiani A. Amante E. Bottini |
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| Affiliation: | (1) 2nd University of Rome School of Medicine, Via Orazio Raimondo, I-00173 Rome, (Italy);(2) Dept of Cell Biology, Laboratory of Genetics, University of Camerino, Camerino, (Italy) |
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| Abstract: | Summary Phenotypes of acid phosphatase with low enzymatic activity (ACP1 A and BA) are correlated with the highest degree of body mass increase observed in a sample of obese children. Since acid phosphatase probably functions as a flavin-mononucleotide phosphatase, differential modulation of flavo-enzyme activity and energy metabolism due to acid phosphatase genetic variability may explain the observed association. |
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| Keywords: | Acid phosphatase genetics of obesity |
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