Prostaglandin-like substances inPropionibacterium acnes II. Stimulatory effect on ovarian cyclic AMP |
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| Authors: | L Hellgren G Selstam J Vincent |
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| Institution: | (1) Department of Dermatology, University of Trondheim, Trondheim, (Norway);(2) Department of Dermatology, Sahlgren's Hospital, Department of Physiology and Department of Structural Chemistry, Faculty of Medicine, University of Göteborg, Göteborg, (Sweden) |
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| Abstract: | Summary The prostaglandin-like substances (PLS) fromPropionibacterium acnes increased the ovarian tissue levels of cyclic AMP (cAMP) approximately 2-fold. The lipid material extracted fromP. acnes thus behaved like PG's of the E-type, and since it is unlikely that other known stimulators of the ovarian cAMP system can be present in the bacterial lipid fraction, these experiments give further evidence in favour of the occurrence of PLS inP. acnes. |
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