Effet des analgésiques non narcotiques sur l'hypotension due à la bradykinine |
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Authors: | B. Vargaftig |
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Affiliation: | (1) Laboratoires Endopancrine, Eragny-sur-Epte, Oise, France |
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Abstract: | Summary Hypotension, induced by intravenous injections of bradykinin in the rabbit, was studied after nontoxic doses of non-narcotic analgesics and other drugs. Non-narcotic analgesics accelerated the speed of return to 50% normal blood pressure, whereas morphine, cyproheptadine, dexamethasone and hydrocortisone had no effect. Phentolamine-treated animals reacted similarly. This acceleration appears to be due to a specific antagonism of the non-narcotic analgesics and not to a liberation of adrenalin. |
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