| 催产素降低卡那霉素耳毒作用的效应 |
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| 引用本文： | 林津,董维嘉.催产素降低卡那霉素耳毒作用的效应[J].辽宁师范大学学报(自然科学版),1996,19(2):132-135. |
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| 作者姓名： | 林津 董维嘉 |
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| 作者单位： | 辽宁师范大学生物系，南京铁道医学院生理室 |
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| 摘 要： | 以耳廓反射阳性的豚鼠为实验材料，记录了对照组（注射卡那霉素）和实验组（注射卡那霉素和催产素）短声（ｃｌｉｃｋ）刺激引起的耳廓反射（Ｐｒｅｙｅｒ’ｓＲｅｆｌｅｘ，ＰＲ）阈值及脑干诱发电位（ＢｒａｉｎｓｔｅｍＥｖｏｋｅｄＲｅｓｐｏｎｓｅ，ＢＳＲ）Ⅲ波阈值．实验结果经ｔ检验发现，注药后两组的ＰＲ阈值及ＢＳＲⅢ波阈值有显著差异，表明催产素具有降低卡那霉素耳毒作用的效应．
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| 关 键 词： | 催产素，卡那霉素，耳廓反射阈值（PR），脑干诱发电位阈值（BSR） |
THE REDUCING EFFECT OF OXYTOCIN ON THE OTOXICITY CAUSED BY KANAMYCIN IN GUINEA PIG |
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| Lin Jin.THE REDUCING EFFECT OF OXYTOCIN ON THE OTOXICITY CAUSED BY KANAMYCIN IN GUINEA PIG[J].Journal of Liaoning Normal University(Natural Science Edition),1996,19(2):132-135. |
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| Authors: | Lin Jin |
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| Abstract: | The experiments were carried on in two groups of Guinea hes. In contrast group,theanimals were injected Kanamycin (40 mg/kg i. m. ) daily for 12 days; in the test group,animalsreceived Kanamycin (400 mg/kg i. m. ) and Oxytocin (10 ig/kg i. m. ) daily for 17 days. Weexamined the threshold of Preyer's Reflex (PR) and the threshold of Brainstem EvokedResponse (BSR) stimulated by click in these two groups before and after drug injection. Theresults showed the Oxytocin has obvious effects of reducing the otoxicity caused by kanamycin. |
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| Keywords: | Oxytocin Kanamycin PR BSR |
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