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Changes in blood tryptophan level during sleep deprivation |
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| Authors: | E Kuhn K Ry?ánek V Brodan H ?pánková |
| Institution: | (1) Metabolism and Nutrition Research Center of the Institute for Clinical and Experimental Medicine, Budejovicka 800, 4-Krc Praha, (Czechoslovakia);(2) 3rd Clinic of Medicine, Faculty Hospital, J. E. Purkyn University, Brno, (Czechoslovakia) |
| Abstract: | Summary Prolonged sleep deprivation elicits a significant elevation of the plasma level of free tryptophan which appears to be involved in increased excretion of 5-HIAA during this state through enhanced 5-HT synthesis. |
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