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Influence of ethanol on thyroxine accumulation in the hypothalamus,pituitary gland and cerebrospinal fluid in the newborn rabbit
Authors:A. B. Ślebodziński
Affiliation:(1) Institute of Animal Physiology and Nutrition, Department of Experimental Pathology of Animals, Polish Academy of Sciences, ul. Grunwaldzka 250, 60-166 Pozna"nacute", (Poland)
Abstract:Summary The effect of ethanol on thyroxine (T4) accumulation in the hypothalamus (H), pituitary gland (P) and cerebrospinal fluid (CSF) has been investigated in 1–15-day-old rabbits. It has been found that H or CSF serum ratios decreased with age by about 2 in the course of 13 postnatal days. Stable T4 resulted in an increase of125I-T4 in H, P and CSF. Ethanol per se caused an increase in transfer and accumulation of radiothyroxine or made the changes after loading animals with carrier T4 more pronounced.
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