Sympatho-inhibitory mechanisms acting at sympathetic ganglia to attenuate hypothalamic-induced pressor effect in the cat |
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Authors: | B Blum J Israeli O Hart M Mihiz M Farchi |
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Institution: | (1) Department of Physiology and Pharmacology, Sackler School of Medicine, Tel Aviv University, 69978 Tel Aviv, (Israel);(2) Dept of Psychology, Northeastern University, Huntington Ave 360, 02115 Boston, Mass, USA |
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Abstract: | Summary Pressor and tachycardic effects induced in the cat by stimulation of a lateral hypothalamic (LH) site, are shown to be mediated by sympathetic ganglia nicotinic receptor, and potentiated under atropine methyl nitrate sympathetic ganglia blockage. It is postulated that a sympatho-inhibitory pathway muscarinic ganglionic mechanism, co-activated by the LH stimulation, attenuates the pressor and tachycardic effects, the potentiation presumably being a manifestation of blockage of that mechanism. |
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Keywords: | Lateral hypothalamus descending sympatho-excitatory and sympatho-inhibitory pathways muscarinic ganglionic receptor attenuation of pressor effect ganglionic inhibition in autonomic function |
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