Si基底上DNA分子的自组装

利用自组装方法将DNA分子吸附于Si基底表面, 并通过原子力显微镜（AFM）观察不同质量浓度的DNA溶液在Si基底表面进行自组装后的结构： 当DNA溶液的质量浓度较低时, Si基底表面会吸附单个、 拉伸、 环状的分子; 当DNA溶液的质量浓度为60~160 ng/μL时, 在Si基底表面会形成网状结构; 当DNA溶液的质量浓度超过200 ng/μL时, 仅形成DNA薄膜. 实验结果表明, 可以利用该方法制作基于Si材料的DNA分子器件.

Self-Assembly of DNA Molecules on Si Substrate

DNA was attached onto Si substrate by self assembly. The AFM images show that the structures of DNA on Si substrate de
pended on the concentration of DNA solution: at a low concentration of DNA, the single, stretched, cricular DNA molecules were absorbed on Si substrate; at 60~160 ng/μL DNA, the DNA network structures were formed; at a concentration of DNA higher than 200 ng/μL, DNA film could just form. These results suggest that it is possible to develop a DNA moleculedevice by this method.