| Pd/C催化水合肼还原法制备邻氨基苯酚 |
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| 引用本文： | 韦长梅.Pd/C催化水合肼还原法制备邻氨基苯酚[J].淮阴师范学院学报(自然科学版),2007,6(3):233-236. |
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| 作者姓名： | 韦长梅 |
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| 作者单位： | 淮阴师范学院,化学系,江苏省低维材料化学重点建设实验室,江苏,淮安,223300 |
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| 基金项目： | 江苏省重点建设实验室基金资助项目(JSKC06028) |
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| 摘 要： | 采用在Pd/C催化下水合肼还原邻硝基苯酚的方法制备邻氨基苯酚,研究了反应温度、催化剂用量和还原剂用量对反应产物收率的影响.优化条件为:95%乙醇为溶剂,0.010 g质量分数为10%的Pd/C催化下,1.300 g质量分数为85%的水合肼还原1.390 g邻硝基苯酚,在75~80℃下反应4 h后,反应粗产物用95%乙醇重结晶得邻氨基苯酚0.95 g,收率为87.16%.目标产品通过了红外、紫外、氢核磁共振和质谱表征.
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| 关 键 词： | 邻氨基苯酚 邻硝基苯酚 还原 水合肼 |
| 文章编号： | 1671-6876（2007）03-0233-04 |
| 修稿时间： | 2007-04-30 |
Preparation of 5-Aminoquinolinol with Hydrazine Hydrate Reduction Method in Presence of Pd/C Catalyst |
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| WEI Chang-mei.Preparation of 5-Aminoquinolinol with Hydrazine Hydrate Reduction Method in Presence of Pd/C Catalyst[J].Journal of Huaiyin Teachers College(Natrual Science Edition),2007,6(3):233-236. |
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| Authors: | WEI Chang-mei |
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| Institution: | Department of Chemistry, Huaiyin Teachers College, Jangsu Key Laboratory for Chemistry of Low-Dimenional Materials, Huaian Jangsu 223300, China |
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| Abstract: | The application and synthetic methods of o-aminophenol were introduced in this paper.o-Aminophenol was prepared by the reductione of o-nitrophenol with hydrazine hydrate as reductant under catalysis of Pd/C.The infections of reaction's temperature,the amount of catalyst agent and reducing agent on the yield of reaction were researched.The optimum conditions for o-aminophenol synthesis were obtained as follows:1.390g o-nitrophenol was reduced by 1.300g hydrazine hydrate(mass fraction of 85%)for 4 h at 75～80℃ by the catalysis of 0.010g Pd/C(mass fraction of 10%)and the solvent of ethanol.The crude product was recrystallized by the 95% ethanol to get 0.95g o-aminophenol with yield of 87.16%.The target compound was characterized by IR、UV、1H NMR and MS. |
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| Keywords: | o-aminophenol o-nitrophenol reduce hydrazine hydrate |
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