Diabete da allossana

Summary Insulin deficiency induced by alloxan treatment reduces cocarboxylase activity in the liver of rat. Such enzymatic activity, however, is brought back to the normal speed by fructose injection. It is suggested that fructose, the turn-over of which in diabetic animals is normal, may be capable of furthering the synthesis of A.T.P. and enhancing phosphorylation of thiamine into cocarboxylase.

---

---

Nota N^o 1; Rapporti fra utilizzatione del fruttosio ed attività cocarbossilasica.