Effect of pretreatment with acetylsalicylate on surgical bleeding and peroperative mortality in rats undergoing kidney transplantation |
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Authors: | I Reyers M B Donati G de Gaetano |
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Institution: | (1) Laboratory of Cardiovascular Pharmacology and Laboratory for Haemostasis and Thrombosis Research, Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, I-20157 Milano, Italy |
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Abstract: | Summary 42 rats were pretreated with L-ASA before kidney transplantation, 43 rats acted as controls. 9 rats with L-ASA. but no control rats, died with i.p. haemorrhage. However, in animals surviving the operation, the intraoperative blood loss did not differ significantly between the 2 groups. |
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