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Histamine as an extremely potent releaser of vasopressin in the rat |
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| Authors: | J. Dogterom Tj. B. van Wimersma Greidanus D. De Wied |
| Affiliation: | (1) Netherlands Central Institute for Brain Research, Ijdijk 28, Amsterdam-0, The Netherlands;(2) Present address: Rudolf Magnus Institute for Pharmacology, Medical Faculty, University of Utrecht, Vondellaan 6, Utrecht, The Netherlands |
| Abstract: | Summary Intraperitoneal and intraventricular injection of histamine induces a very fast and high elevation of vasopressin in rat plasma as determined by radioimmunoassay. The effects are dose and time related. The intraventricular injection is more effective with regard to time and dose than the intraperitoneal injection. |
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