应用磁共振扩散张量成像对正常人脑白质各向异性的初步研究

目的 利用磁共振扩散张量成像(DTI)技术,研究正常人脑白质的各向异性的正常变化.方法 随机选择20例正常志愿者进行磁共振扩散张量成像,测定双侧内囊前后肢、内囊膝部、外囊、半卵圆中心及胼胝体膝部和压部的FA值,并进行统计学分析.结果 人脑白质中FA值在胼胝体、内囊、外囊、半卵圆中心间均有显著性差别(P＜0.05).胼胝体膝部与压部、内囊前后肢与膝部无显著性差别.结论 DTI技术可以清楚地显示脑白质的解剖结构,通过FA值,能较好地反映组织的各向异性的变化.

A Preliminary Study on the Anisotropy of Normal Cerebral White Matter by MR Diffusion Tensor Imaging

Objective To evaluate the changes of fractional anisotropy in normal cerebral white matter by using diffusion tensor imaging(DTI).Methods 20 healthy volunteers were selected and underwent DTI examination,and fractional anisotropy(FA) of the bilateral cerebral white matter were measured and analyzed statistically.Results There were significant difference of FA values in the corpus callosum,the internal capsule,the external capsule and centrum semiovale,and no difference between the genu and splenium of corpus callosum,also no significant difference in anterior limb,posterior limb and genu of the internal capsule.Conclusion DTI can display the changes of anisotropy of tissues,is very useful in showing the structure of the cerebral white matter.