Influence of cosmic radiation on lymphocyte micronucleus, serum lipid peroxide and antioxidation capacity in aircrew members |
| |
Authors: | Weiru Chen Yingjin Feng Jiangkuang Liu Haili Zhang Ying Guo Yan Zhang Shiying Duan Xintao Peng Tianping Sun Baoshan Jia Junxian Zhao Hua Li |
| |
Institution: | (1) Department of Aeromedicine, Civil Aviation University of China, 300300 Tianjin, China;(2) College of Medicine, Nankai University, 300071 Tianjin, China;(3) Xinjiang Aviation Company, 830016 Urumuqi, China |
| |
Abstract: | This study looks into the influence of cosmic radiation at high altitudes on human bodies. Results reveal that the cytokinesis-block
micronuclei (CBMN) and conventional cultured micronuclei in peripheral blood lymphocytes, serum levels of lipid peroxide,
Superoxide dismutase, and the total antioxidation capacity by chemical colorimetry all increased significantly in aircrew
members. There exists a linear relationship between the CBMN and the average annual effective doses of radiation received
or the average annual flying hours. With both of them, a trend shows that the serum lipid peroxide levels increase as well.
Either the lipid peroxide or CBMN can sensitively reflect the recent changes in flight load. These findings indicate that
cosmic radiation impairs the stability of chromosomes and genome, and induces lipid oxidative damage in aircrews; Lymphocyte
CBMN and serum lipid peroxide can be used as monitoring indicators in the cosmic radiation protection for aircrew members. |
| |
Keywords: | cosmic radiation aircrew micronucleus lipid peroxide antioxidation capacity |
本文献已被 万方数据 SpringerLink 等数据库收录! |
| 点击此处可从《中国科学通报(英文版)》浏览原始摘要信息 |
| 点击此处可从《中国科学通报(英文版)》下载免费的PDF全文 |