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Improved conversion of methanol to single-cell protein by Methylophilus methylotrophus |
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| Authors: | J D Windass M J Worsey E M Pioli D Pioli P T Barth K T Atherton E C Dart D Byrom K Powell P J Senior |
| Abstract: | The glutamate dehydrogenase gene of Escherichia coli has been cloned into broad host-range plasmids and can complement glutamate synthase mutants of Methylophilus methylotrophus. Assimilation of ammonia via glutamate dehydrogenase is more energy-efficient than via glutamate synthase, thus the recombinant organism converts more growth substrate, methanol, into cellular carbon. |
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