Structure of two biologically active sesquiterpenoid amino-quinones from the marine spongeDysidea avara |
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Authors: | G Cimino S De Rosa S De Stefano L Cariello L Zanetti |
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Institution: | (1) Istituto per la Chimica di Molecole d'Interesse Biologico, CNR, Via Toiano 2, Arco Felice, Naples, Italy;(2) Biochemistry Laboratory, Stazione Zoologica, Villa Comunale, I-80121 Naples, Italy |
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Abstract: | Summary The structures of 2 minor constituents of the marine spongeDysidea avara, which induce developmental aberrations in sea-urchin eggs, are described. The structures were confirmed also by a simple synthesis from avarol (1).Acknowledgments. The authors wish to thank Mr A. Crispino for his skillfull laboratory technical assistance. Thanks are also due to Mr C. Di Pinto (NMR) and Mr A. Milone (MS). |
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