Immunomodulating effects in vitro of a hydroxythiazolobenzimidazole in the absence of mitogenicity |
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Authors: | G. H. Warren L. Mills H. Friedman |
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Affiliation: | (1) Departments of Microbiology, Wyeth Laboratories, Inc., P.O. Box 8299, 19101 Philadelphia, (Pennsylvania), (USA);(2) Albert Einstein Medical Center, 19141 Philadelphia, (Pennsylvania), (USA) |
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Abstract: | Summary Wy-13, 876, a hydroxythiazolobenzimidazole, enhanced in vitro antibody formation by mouse spleen cells immunized with sheep red blood cells. The optimal dose was 25–50 g/culture. The compound did not have a mitogenic effect at any dose. |
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