| 蚕豆根尖微核技术测定美洲大蠊提取物的抑突变性 |
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| 引用本文： | 马志敏,杨雄波,季守莲,刘光明,施贵荣.蚕豆根尖微核技术测定美洲大蠊提取物的抑突变性[J].大理学院学报,2008,7(12):25-27. |
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| 作者姓名： | 马志敏 杨雄波 季守莲 刘光明 施贵荣 |
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| 作者单位： | 1. 大理学院公共卫生学院,云南大理,671000
2. 大理学院药学院,云南大理,671000 |
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| 基金项目： | 国家自然科学基金资助项目
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大理学院科研基金资助项目
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| 摘 要： | 目的：了解美洲大蠊提取物的抑突变性。方法：将来自大理市周边七里桥村和小关邑村的两份蚕豆，分别随机分成4组：美洲大蠊组、美洲大蠊＋环磷酰胺组、阴性对照组、阳性环磷酰胺组，采用蚕豆根尖微核技术进行检测。结果：七里桥村和小关邑村蚕豆之间微核率无统计学意义（P〉0．05）。用美洲大蠊提取物处理过的蚕豆与阳性对照组之间微核率有统计学意义（P〈0．01）。结论：美洲大蠊提取物对蚕豆根尖微核率有抑制作用。
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| 关 键 词： | 美洲大蠊提取物 蚕豆 微核试验 环磷酰胺 抑突变性 |
Vica-micronucleus Test in Checking the Anti-mutation of Mixed Ingredients of Periplaneta Americana |
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| MA Zhimin,YANG Xiongbo,JI Shoulian,LIU Guangming,SHI Guirong.Vica-micronucleus Test in Checking the Anti-mutation of Mixed Ingredients of Periplaneta Americana[J].Journal of Dali University,2008,7(12):25-27. |
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| Authors: | MA Zhimin YANG Xiongbo JI Shoulian LIU Guangming SHI Guirong |
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| Institution: | MA Zhimin1,YANG Xiongbo1,JI Shoulian1,LIU Guangming2,SHI Guirong2 |
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| Abstract: | Objective:To investigate the anti-mutation of Periplan-mericana Linnaeus.Methods:Broad beans from Qiliqiao Village and Xiaguanyi Village in Dali were divided into 4 groups,cyclophosphamide group,negative control group,Periplan-mericana Linnaeus group,and Periplan-mericana Linnaeus plus cyclophosphamide group.The purpose was to check the anti-mutation of Periplan-mericana Linnaeus by means of vica-micronucleus test.Results:Compared with the group cyclophosphamide,there was a statistical significance(P<0.01).Conclusion:Periplan-mericana Linnaeus can inhibit the mutation induced by cyclophosphamide,and thus it has a positive role in preventing the growth of tumors. |
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| Keywords: | Periplaneta american Vicia faba micronucleus test cyclophosphamide anti-mutation |
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