首页 | 本学科首页   官方微博 | 高级检索  
     


In vitro systems in the study of peroxisomal protein import
Authors:A. Baker
Affiliation:(1) Centre for Plant Biochemistry and Biotechnology, University of Leeds, LS2 9JT Leeds, UK
Abstract:Our level of understanding of peroxisome biogenesis in comparison with other cellular organelles is rudimentary, yet the fragments of information available indicate that the targeting and import of peroxisomal proteins occur by fundamentally different mechanisms. Genetic studies have identified a number of genes required for peroxisome assembly, but in most cases the functions of the gene products remain unknown. In vitro protein translocation systems have played a prominent role in unravelling the biochemistry of protein translocation into other organelles. This review considers some of the requirements for establishing a bona fide peroxisomal import assay and discusses the findings which have emerged as a result of using such experimental systems.
Keywords:Peroxisomes  glyoxysomes  in vitro protein translocation assay  targeting signals  organelle biogenesis
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号