Effet de l'ablation partielle ou totale du tissu rénal sur l'hypertension rénovasculaire chez le rat

Summary Arterial hypertension, elicited in the rat by partial renal artery constriction, appears faster and affects more animals when the controlateral kidney is removed simultaneously. Excision of the ischemic kidney after hypertension of 1 to 3 weeks duration is not followed by any fall of blood pressure during the first 24 h. If the arterial constriction is not accompanied by controlateral nephrectomy, hypertension disappears after removal of the ischemic kidney, diminishes after bilateral nephrectomy and is increased by excision of the un-touched kidney.

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Ce travail bénéficie du soutien financier du Fonds National Suisse de la Recherche Scientifique (crédit No. 5315) et d'un crédit de recherche de Robapharm SA, Bâle.