血清硒元素与妊娠期糖尿病相关性分析

目的探析血清硒元素与妊娠期糖尿病相关性.方法2020年3月—2021年9月，依据入选标准选取360例孕妇为研究对象，分为对照组和观察组，对照组为180名体检正常的孕妇，GDM诊断结果为阴性；观察组为180名GDM诊断结果为阳性的孕妇，接受住院治疗.对同组孕妇不同妊娠期硒元素水平、两组孕妇相同妊娠期硒元素水平、两组孕妇妊娠结局和新生儿结局进行对比.结果两组孕晚期孕妇血清硒元素水平显著低于孕中期和孕早期孕妇（P<0.05），孕中期孕妇血清硒元素水平显著低于孕早期孕妇（P<0.05），并且观察组不同妊娠期孕妇硒元素水平均显著低于对照组（P<0.05）；观察组不良妊娠结局发生率和不良新生儿结局发生率均高于对照组.结论血清硒元素与妊娠期糖尿病具有较强的相关性，因此在妊娠期间对孕妇进行微量元素检测，为孕妇补充硒元素具有积极意义.

Correlation Analysis of Serum Selenium and Gestational Diabetes Mellitus

Objective:To explore the correlation between serum selenium and gestational diabetes mellitus.Methods:From March 2020 to September 2021,360 pregnant women were selected as subjects according to the inclusion criteria,180 of whom were normal physical examination subjects with negative GDM diagnosis and were classified as control group,and 180 with positive GDM diagnosis received hospitalization and were classified as observation group.Methods:Selenium levels in different pregnancy periods of the same group and the selenium levels in same pregnancy period of the two groups were compared.Pregnancy outcomes and neonatal outcomes of the two groups were compared.Results:The serum selenium level of pregnant women in the third trimester was lower than that in the middle and early trimesters in the two groups (P<0.05),and the serum selenium level of pregnant women in the second trimester was lower than that in the early trimesters in the observation group (P<0.05).The incidence of adverse pregnancy outcomes and adverse neonatal outcomes in the observation group were higher than those in the control group.Conclusion:There is a strong correlation between serum selenium and gestational diabetes mellitus,and it is of positive significance for pregnant women to supplement selenium by detecting trace elements during pregnancy.