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Identification of a testosterone-dependent unique volatile constituent of male mouse urine: 7-exo-ethyl-5-methyl-6,8-dioxabicyclo[3.2.1]-3-octene
Authors:M Novotny  F J Schwende  D Wiesler  J W Jorgenson  M Carmack
Institution:(1) Department of Chemistry, Indiana University, 47405 Bloomington, Indiana, USA;(2) Present address: Upjohn Pharmaceuticals, Kalamazoo, Michigan, USA;(3) Present address: Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina, USA
Abstract:Summary Investigations regarding the chemical composition of the volatiles in male mouse urine have recently enabled the structural elucidation of a hitherto unreported urinary component, 7-exo-ethyl-5-methyl-6,8-dioxabicyclo3.2.1]-3-octene. This compound's uniqueness to mouse urine and its dependence on testosterone levels in the male suggest its probable role as a mouse pheromone or pheromone adjuvant.
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