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Demonstration of a tryptaminergic mechanism in the rat beta-cell. |
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| Authors: | O Pulido A de Bold M de Bold S Bencome |
| Abstract: | Yellow 5-HT fluorescence has been histochemically demonstrated in rat pancreatic islet cells in animals injected with L-5-HTP with or without pretreatment with the monoaminoxidase inhibitor nialamide. This fluorescence was not observed after inhibition of the aromatic amino acid decarobxylase. The results strongly suggest the presence of a tryptaminergic mechanism in the rat islet cells. |
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