望江南化学成分分离和结构鉴定

研究望江南的化学成分. 利用硅胶、Sephadex LH-20柱色谱及重结晶等方法进行分离纯化,根据理化性质和1H-NMR、13C-NMR等波谱数据进行结构鉴定. 从望江南种子中用体积分数为95%的乙醇提取物的氯仿部分分离得到5个化合物,分别鉴定为大黄素甲醚(1),豆甾醇(2),5,7'-二聚大黄素甲醚(3),1-棕榈酸单甘油酯(4),豆甾醇-3-β-D-吡喃葡萄糖苷(5). 其中,化合物3,4,5为首次从望江南中分离得到. 

Isolation and Structure Identification of Chemical Constituents from Cassia occidentalis

The chemical constituent of Cassia occidentalis is studied in this work. The compounds were isolated by column chromatography on silica gel, Sephadex LH-20 and recrystallization. Their structures were determined on the basis of physico-chemical properties and spectroscopic methods such as 1H-NMR and 13C-NMR. Five compounds were isolated from the chloroform fraction of 95% ethanolic extract of Cassia occidentalis seeds. They were identified as physcion (1); stigmasterol (2); 5,7'-biphyscion (3); monopalmitin (4); stigmasterol-3-β-D-glucopyranoside(5), respectively. The last three compounds (3,4 and 5) are isolated from the Cassia occidentalis for the first time.