Wound healing properties of naphthaquinone pigments fromAlkanna tinctoria |
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| Authors: | V P Papageorgiou |
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| Institution: | (1) Laboratory of Organic Chemistry, Department of Chemical Engineering, Polytechnical School, Aristotle University, Thessaloniki, (Greece) |
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| Abstract: | Summary From the roots ofAlkanna tinctoria Tausch, the alkannin esters of the following acids were isolated and identified:  ,-dimethylacrylic acid, -acetoxy-isovaleric acid, isovaleric acid, and angelic acid. These esteric pigments showed excellent wound healing properties in a clinical study on 72 patients with ulcus cruris.I thank Dr A. Winkler, Heidberg Hospital and Prof. K. Kanitakis, Aristotle University, for the clinical studies. Prof. A. Sagredos, Aristotle University, for his help and Dr C. Gairola, Tobacco and Health Research Institute, for the mutagenicity tests. I also thank Dr G. A. Digenis and Dr L. Hurley, University of Kentucky, College of Pharmacy, for their critical reviews and comments. |
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