Gefässkonstriktion durch synthetisches Bradykinin und ihre pharmakologische Beeinflussbarkeit

Summary The divided hindlimb of the cat was perfused through the femoral artery with tyrode solution. Synthetic bradykinin administered via the artery elicits a vasoconstriction,- and-sympathicolytics decrease the vasoconstriction, cocain and guanethedin emphasize it, whilst iproniacid and reserpin have no influence on it. It is assumed that bradykinin acts directly on adrenergic structures of the vessels of the hindlimb of the cat.