Somatic cell hybrids producing inhibitors of melanotic melanoma tyrosine hydroxylase |
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Authors: | A. A. Hakim |
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Affiliation: | (1) Departments of Surgery, Oral Diagnosis, Physiology and Biophysics, University of Illinois at the Medical Center, 60680 Chicago, Illinois, USA;(2) Present address: 180 Longwood Drive, 60901 Kankakee, (Illinois, USA) |
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Abstract: | Summary Splenic lymphocytes from BALB/c mice pre-immunized with purified tyrosine hydroxylase (TH) were fused with murine myeloma N/1 cells. Supernatants of only 2 from large number of cloned cell hybrids contained an inhibitor of TH. |
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