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Somatic cell hybrids producing inhibitors of melanotic melanoma tyrosine hydroxylase
Authors:A. A. Hakim
Affiliation:(1) Departments of Surgery, Oral Diagnosis, Physiology and Biophysics, University of Illinois at the Medical Center, 60680 Chicago, Illinois, USA;(2) Present address: 180 Longwood Drive, 60901 Kankakee, (Illinois, USA)
Abstract:Summary Splenic lymphocytes from BALB/c mice pre-immunized with purified tyrosine hydroxylase (TH) were fused with murine myeloma N/1 cells. Supernatants of only 2 from large number of cloned cell hybrids contained an inhibitor of TH.
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