Distribution of14C after topical application of14C-labeled 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) in mice |
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| Authors: | H. S. Zackheim R. J. Feldmann C. Lindsay H. I. Maibach |
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| Affiliation: | (1) Department of Dermatology, University of California Medical Center, 94143 San Francisco, California, USA |
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| Abstract: | Summary Following topical application of14C-labeled 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU, carmustine) to the skin of mice radioactivity was found in all viscera and tissues examined. Exclusive of the gut, highest values were recorded for the liver, kidney and lung.Supported by Public Health Service, grant CA 14825, from the National Cancer Institute, National Institutes of Health, Department of Health, Education and Welfare. |
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