| 丙泊酚联和咪达唑仑用于ICU机械通气镇静治疗的临床观察 |
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| 引用本文： | 邹天雷,赵永茂.丙泊酚联和咪达唑仑用于ICU机械通气镇静治疗的临床观察[J].大理学院学报,2011,10(8):36-38. |
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| 作者姓名： | 邹天雷 赵永茂 |
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| 作者单位： | 大理学院附属医院,云南大理,671000 |
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| 摘 要： | 目的:评价丙泊酚联和咪达唑仑在ICU机械通气镇静治疗中的效果。方法:将69例患者随机分为两组:观察组(丙泊酚-咪达唑仑联和组)35例和对照组(咪达唑仑组)34例,观察两组治疗前后心率、平均动脉压、呼吸、血氧饱和度变化、药物起效时间、停药后苏醒时间、达到满意镇静深度时间及不良反应。结果:两组治疗前后生命体征有明显变化(P<0.05)。观察组药物起效时间、停药后苏醒时间、达到满意镇静深度时间均比对照组短,两组比较差异有统计学意义(P<0.05)。停药后观察组出现恶心2例,对照组6例;观察组出现血压下降6例,对照组5例。结论:丙泊酚和咪达唑仑联用有着很好的镇静效果,不良反应少,可安全有效地应用于ICU机械通气的镇静治疗。
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| 关 键 词： | 丙泊酚 咪达唑仑 机械通气 镇静 |
Clinical Observation of Combined Propofol and Midazolam for Sedation Therapy in ICU Mechanical Ventilation |
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| ZOU Tianlei,ZHAO Yongmao.Clinical Observation of Combined Propofol and Midazolam for Sedation Therapy in ICU Mechanical Ventilation[J].Journal of Dali University,2011,10(8):36-38. |
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| Authors: | ZOU Tianlei ZHAO Yongmao |
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| Institution: | ZOU Tianlei,ZHAO Yongmao(Affiliated Hospital of Dali University,Dali,Yunnan 671000,China) |
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| Abstract: | Objective: To evaluate the effect of combined use of propofol and midazolam for sedation therapy in ICU mechanical ventilation Methods: Sixty-nine patients were randomly divided into two groups: study group(combined propofol and midazolam) with 35 cases and control group(midazolam group) with 34 cases.Heart rate,mean arterial pressure,respiration,oxygen saturation,drug onset time,wake time of drug withdrawal,the time of achieved satisfactory sedation and side effects were observed before and after the treat... |
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| Keywords: | propofol midazolam mechanical ventilation sedation |
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