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Visualisation of lectin binding sites on the surface of human platelets using lectins adsorbed to gold granules
Authors:A T Nurden  M Horisberger  E Savariau  J P Caen
Institution:(1) Unité 150 INSERM, Hôpital Lariboisière, 6, rue Guy Patin, F-75010 Paris, (France);(2) Nestlé Research Department, CH-1814 La Tour-de-Peilz, (Switzerland)
Abstract:Summary Washed human platelets have been incubated with the lectins WGA, ConA and RCA1, adsorbed to differentsized gold particles. Plasma membrane receptors for each lectin were then located by scanning and transmission electron microscopy.Acknowledgments. We would like to thank Mlle Dominique Dupuis for technical assistance. This work was supported in part by grant No. CRL 78.5.128.1 from INSERM.
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