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Chromatin condensation in isolated rat hepatocyte nuclei induced by ribonuclease treatment
Authors:M Derenzini  Annalisa Pession-Brizzi  F Novello
Institution:(1) Istituto di Patologia Generale dell'Università, Via S. Giacomo 14, I-40126 Bologna, (Italy)
Abstract:Summary Ribonuclease treatment of isolated rat hepatocyte nuclei induced a 75% solubilization of hnRNA, a reduction of the qualtity of perichromatin fibrils, and a marked condensation of chromatin.This investigation was supported by grants from C.N.R. (Roma) and by Pallotti's Legacy for Cancer Research.
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